|
KMID : 0379120010290020086
|
|
Korean Journal of Mycology
2001 Volume.29 No. 2 p.86 ~ p.90
|
|
|
Effect of Pleurotus eryngii on the Blood Glucose and Cholesterol in Diabetic Rats
|
|
Lee Shin-Young
Kang Tae-Su
Sung Jae-Mo
Kang Mi-Sun
Kang An-Seok
Shon Hyeong-Rak
|
|
|
Abstract
|
|
|
|
This study was conducted to investigate the effects of Pleurotus eryngii fruiting body on blood glucose and cholesterol levels in streptozotocin-induced diabetic rats. Male Sprague-Dawley rats were used as experimental animals and experimental groups were divided into three groups, consisting of two control groups (diabetic and non-diabetic) and one P. eryngii group. Animals were fed experimental diets for 2 weeks. The values of diet and water intake of P. eryngii group were lower than those of diabetic control group. The body weights of both groin after 2 weeps decreased by 18% as compared with initial values. The level of blood glucose decreased significantly by 16.9% in P. eryngii group as compared with diabetic control group, and there was a significant difference in glycosylated hemoglobin (GHb) level between both groups. The levels of total-cholesterol, LDL-cholesterol in plasma and atherasclerotic index were not significantly different between both groups. However the level of HDL-cholesterol increased significantly by 28% in P. eryngii group as compared with diabetic control group. These results suggested that fruiting bodies of P. eryngii exert blood glucose-lowering effect in streptozotocin-induced diabetic rats.
|
|
|
KEYWORD
|
|
|
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
 
|